About
Dr Marta Melé is the Group Leader of the Transcriptomics and Functional Genomics Lab at the Barcelona Supercomputing Center (BSC). With a PhD in Biomedical Research from Pompeu Fabra University, her research positions include a postdoctoral fellowship at Harvard University and the Broad Institute. Her work has significantly contributed to the understanding of transcriptomic regulation, genetic variation and human phenotypic diversity, with an H-index of 27 and over 12,800 citations.
Marta has secured numerous grants, such as the Chan Zuckerberg Initiative award, and received the L’Oréal-UNESCO For Women in Science Award. She actively promotes women in computational biology through initiatives like Bioinfo4Women and serves on multiple scientific advisory boards. An accomplished mentor and speaker, her research continues to push the boundaries of genomics and computational biology.
Research group website
Research interests
Marta’s research group is focused on uncovering how the human transcriptome is regulated in the context of health and disease. Dynamic regulation of the transcriptome is central to the development and maintenance of an organism’s phenotype. This includes morphological features, physiological attributes and susceptibility to diseases. This research aims to understand how changes in the transcriptome explain phenotypic differences between individuals across factors of age, sex, genetic ancestry and disease susceptibility. Understanding the molecular drivers of human phenotypic variation is crucial for treating patients according to their individual needs and challenging generalised disease categories. This research has the ultimate goal of advancing the biomedical field towards personalised medicine. Transcriptomics, genomics, gene expression, bioinformatics, computational biology, autoimmune diseases, sex differences, aging and development are all topics of interest within this research.
Social Media
